In the UCLH analysis of patients requiring re-step-up dosing of a bispecific antibody after a prolonged treatment delay, which finding was reported?
CRS was infrequent and limited to grade 1–2, with no ICANS; all cases occurred early in treatment in patients who had not achieved VGPR
CRS occurred in most patients, with grade ≥3 events most common in those who had achieved VGPR or better
CRS was rare, but ICANS occurred in around a quarter of patients, mainly after delays late in the treatment course